Quinolines and derivatives

Aromatic organic heterocyclic compounds that contain a benzene ring fused with a six-membered ring that contains one nitrogen atom and five carbon atoms. Includes compounds that are derived from quinolines.

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3,421 – 3,435 of 4,473 results

3,421

Medchemexpress LLC AL-611 | 2481279-61-0 | 99.9% | C25H33F2N6O8P | 1 ML

AL-611 is an HCV NS5B polymerase inhibitor with an EC50 of 5 nM, intended for research use only.

Molecular weight of 614.54.
Purity of 99.93%.
Appears as a solid, white to off-white.
Soluble in DMSO (125 mg/mL).
Store powder at -20°C for up to 3 years.
Store in solvent at -80°C for 6 months, or -20°C for 1 month.
Exhibits CC50 > 100 μM and EC50 0.005 μM in Huh-7 cells.
Involved in a Phase 1 clinical trial for Hepatitis C (NCT03253471).

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3,422

Medchemexpress LLC TNF-α (31-45), human | 144796-71-4 | 99.99% | 1667.87 | 5 MG

TNF-α (31-45), human is a potent NF-kB pathway activator and a proinflammatory cytokine that induces necrosis or apoptosis. It stimulates the NF-κB pathway via TNFR2, promoting cancer growth, invasion, and metastasis.

Potent NF-κB pathway activator
Induces necrosis or apoptosis
Stimulates NF-κB pathway via TNFR2
Promotes cancer growth, invasion, and metastasis
High purity (99.99% by HPLC)
Molecular weight of 1667.87
White to off-white solid appearance
Sequence: Arg-Arg-Ala-Asn-Ala-Leu-Leu-Ala-Asn-Gly-Val-Glu-Leu-Arg-Asp
Soluble in water at 50 mg/mL (requires ultrasonic)

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3,423

Medchemexpress LLC (S)-4-isopropyl-3-methyl-2-(3-methylpiperidine-1-carbonyl)isoxazol-5(2H)-one | 654059-21-9 | 99.8% | 266.34 g/mol | C14H22N2O3 | 100 MG

BAY 59-9435 (HSL-IN-2) is a potent, selective small-molecule inhibitor of hormone-sensitive lipase (HSL) with an IC50 of 0.023 μM. It exhibits cellular activity (28 nM in 3T3-L1 cells for inhibition of forskolin-stimulated lipolysis) and is supplied as a high-purity solid for research use, with recommended storage conditions to maintain stability.

Potent and selective HSL inhibition (IC50 0.023 μM).
Demonstrated cellular activity in adipocyte assays (28 nM).
High purity suitable for biochemical and cellular studies.
Stable as powder under recommended storage conditions.
Soluble in DMSO for assay preparation.

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3,424

Medchemexpress LLC Trimethyl[2,3-(dioleyloxy)propyl]ammonium chloride | 104162-48-3 | MFCD00145456 | 98.0% | 670.57 g/mol | C42H84ClNO2 | 50 MG

Trimethyl[2,3-(dioleyloxy)propyl]ammonium chloride is a quaternary ammonium, lipid-like reagent used in life-science research. It acts as an amphiphilic cationic lipid for formulation and membrane studies, and can be used as a surfactant or helper lipid in experimental delivery systems. The material is supplied with product documentation and handling information and is intended for research use only.

Quaternary ammonium headgroup provides cationic charge.
Two dioleoyl chains confer lipid-like amphiphilicity.
Amphiphilic character supports bilayer and vesicle formulation.
Soluble in common organic solvents for formulation workflows.
Provided with documentation and safety data for lab use.
Store sealed and away from moisture; refrigerate for prolonged stability.

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3,425

Medchemexpress LLC Mal-amido-(CH2COOH)2 | 207613-14-7 | 99.2% | 284.22 g/mol | C11H12N2O7

Mal-amido-(CH2COOH)2 compound 7a is a maleimidoethyl-containing intermediate for hydrophilic ADC linker[1]

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3,426

Medchemexpress LLC Pyrroloquinoline quinone disodium salt | 122628-50-6 | 98.0% | 374.17 g/mol | C14H4N2Na2O8 | 10 MG

Pyrroloquinoline quinone disodium salt is a water-soluble redox cofactor used as a research reagent in studies of cellular metabolism, mitochondrial function, and oxidative stress. The disodium salt form enhances solubility for aqueous assays and small-scale formulations, and is typically supplied with high purity for experimental reproducibility.

Water-soluble form suitable for aqueous assays.
Acts as a redox cofactor for metabolism and mitochondrial studies.
High purity supports reproducible experimental results.
Appropriate for biochemical and cell biology applications.
Available in small quantities for screening and pilot studies.

Pricing & Availability

3,427

Medchemexpress LLC 5'-O-(4,4'-dimethoxytrityl)-2'-O-methyluridine | 103285-22-9 | MFCD00274123 | 98.0% | 560.59 g/mol | C31H32N2O8 | 10 G

5'-O-(4,4'-Dimethoxytrityl)-2'-O-methyluridine is a DMT-protected 2'-O-methyl uridine nucleoside used as a building block and intermediate for solid-phase oligonucleotide synthesis and for research on modified RNA. It is supplied as a high-purity solid or as a DMSO solution to facilitate incorporation into synthesis workflows.

DMT-protected 2'-O-methyl uridine suitable for oligonucleotide synthesis.
High purity (98.03%) for reliable reactions.
Available as powder and 10 mM solution in DMSO for flexibility.
Long-term storage stability when kept at recommended temperatures.
Datasheet, COA, and SDS available to support quality control.

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3,428

TARGETMOL CHEMICALS INC AP 18 5MG

Also available in 1mg 2mg 10mg 25mg 50mg 100mg 500mg and bulk. Please contact Fisher for quotes. AP-18 is a potent and selective TRPA1 inhibitor. AP-18 inhibits activation of TRPA1 induced by 50 μM Cinnamaldehyde with an IC50 of 3.1 μM and 4.5 μM for human and mouse TRPA1 respectively. AP-18 could reverse complete Freund's adjuvant (CFA)-induced mechanical hyperalgesia in mice. AP-18 could attenuate Yo-Pro uptake induced by 30 μM AITC in a concentration-dependent manner (IC50= 10.3 μM). purity: 99%

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3,429

Medchemexpress LLC Mal-amido-PEG9-acid | 2112731-43-6 | 99.5% | 250 MG

Mal-amido-PEG9-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. These PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. This product is for research use only and has not been fully validated for medical applications.

PEG-based linker
Used in synthesis of PROTACs
Facilitates selective degradation of target proteins
Utilizes ubiquitin-proteasome system
Contains two ligands connected by a linker

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3,430

Medchemexpress LLC Pomalidomide-amido-C5-PEG2-C6-chlorine | 1835705-69-5 | 98.8% | 594.10 | 50 MG

Pomalidomide-amido-C5-PEG2-C6-chlorine is a derivative of Pomalidomide, intended for research use only. This product is supplied as a white to off-white solid.

High purity of 98.75%
Molecular weight of 594.10
Stable under recommended storage conditions
Store at 4°C under nitrogen
For research use only

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3,431

TARGETMOL CHEMICALS INC THONZONIUM BROMIDE 50MG

Also available in 5 mg 10 mg 25 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Thonzonium bromide is a mono-cationic surfactant that is structurally similar to Farnesol as an antimicrobial agent. It inhibits proton transport in a dose-dependent manner (EC50=69 uM). It inhibits RANKL-induced osteoclast formation and bone resorption in vitro and prevents LPS-induced bone loss in vivo. purity: 99%

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3,432

Medchemexpress LLC 2,6-Dimethoxy-1,4-benzoquinone | 530-55-2 | 168.15 | 1 ML

2,6-Dimethoxy-1,4-benzoquinone | 530-55-2 | 168.15 | 1 ML

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3,433

Medchemexpress LLC 1-tert-Butyl-3-ethoxybenzene | 133073-81-1 | 95.0% | C12H18O | 500 MG

1-tert-Butyl-3-ethoxybenzene is a drug intermediate for the synthesis of various active compounds. This product is intended for research use only and is not for human or medical applications.

A drug intermediate for the synthesis of various active compounds.
For research use only.
Appearance: Liquid.
Color: Light yellow to light brown.
Chemically stable under recommended storage conditions.

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3,434

Ambeed Methyl 4bromo3methylbenzoate

Methyl 4-bromo-3-methylbenzoate, 148547-19-7, 98%

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3,435

Ambeed Benzyl 3oxocyclobutyl carbama

Benzyl (3-oxocyclobutyl)carbamate, 130369-36-7, 97%

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Quinolines and derivatives

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Medchemexpress LLC AL-611 | 2481279-61-0 | 99.9% | C25H33F2N6O8P | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC TNF-α (31-45), human | 144796-71-4 | 99.99% | 1667.87 | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC (S)-4-isopropyl-3-methyl-2-(3-methylpiperidine-1-carbonyl)isoxazol-5(2H)-one | 654059-21-9 | 99.8% | 266.34 g/mol | C14H22N2O3 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Trimethyl[2,3-(dioleyloxy)propyl]ammonium chloride | 104162-48-3 | MFCD00145456 | 98.0% | 670.57 g/mol | C42H84ClNO2 | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Mal-amido-(CH2COOH)2 | 207613-14-7 | 99.2% | 284.22 g/mol | C11H12N2O7 Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Pyrroloquinoline quinone disodium salt | 122628-50-6 | 98.0% | 374.17 g/mol | C14H4N2Na2O8 | 10 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 5'-O-(4,4'-dimethoxytrityl)-2'-O-methyluridine | 103285-22-9 | MFCD00274123 | 98.0% | 560.59 g/mol | C31H32N2O8 | 10 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

TARGETMOL CHEMICALS INC AP 18 5MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Mal-amido-PEG9-acid | 2112731-43-6 | 99.5% | 250 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Pomalidomide-amido-C5-PEG2-C6-chlorine | 1835705-69-5 | 98.8% | 594.10 | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

TARGETMOL CHEMICALS INC THONZONIUM BROMIDE 50MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 2,6-Dimethoxy-1,4-benzoquinone | 530-55-2 | 168.15 | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 1-tert-Butyl-3-ethoxybenzene | 133073-81-1 | 95.0% | C12H18O | 500 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More